Chondroblastoma-Like Soft-Tissue Chondroma of the Hand: A Case Report.

We present a case of chondroblastoma-like chondroma (CLC) of soft tissue that manifested as a palmar mass on the left hand of an 84-year-old man. Physical examination, imaging investigation, and needle biopsy initially suggested a giant cell tumor of the tendon sheath, until a correct diagnosis was made based on excised specimen histology. The patient underwent a marginal excision for soft-tissue mass removal. Follow-up examination showed excellent relief of symptoms, and full hand mobility was regained. The diagnosis of CLC is challenging because the radiographic and pathological features vary. Therefore, we highly emphasize the importance of utilizing excisional tissue for histopathological assessment in atypical chondroma presentations.