Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor.

Journal: Stem Cell Research
Published:
Abstract

This study describes the characterization of one induced pluripotent stem cell line (iPSC) from a healthy female. It is crucial to use iPSCs derived from healthy individuals as controls in genetic disease studies. Thus, we established a human iPSC cell line derived from healthy people. The iPSC cell line was generated in our lab from the peripheral blood mononuclear cells (PBMCs) of a 28-year-old girl. The generated hiPSC line is free of episomal vectors, has a normal karyotype, expresses pluripotency markers and can differentiate into three germ layers in vivo.

Authors
Lingyuan Min, Yongtian Yin, Qingyang Zhao, Shiyuan Wang