A Case of Invasive Aspergillosis Involing Orbital Apex and Optic Nerve Sheath.

Spread of fungal infection neurally is a rare phenomenon. Hereby we report a case of fifty year old diabetic female with primary optic atrophy and aspergillosis of orbital apex and optic nerve sheath. In this case fungal debris was found in sphenoid sinus, orbital apex and optic nerve sheath. This patient had mild proptosis on left eye. This is a rare condition of fungal growth in the optic nerve sheath. Radiological investigation revealed bony erosion in posterior wall of sphenoid sinus. Functional endoscopic sinus surgery was done and sample sent for KOH mount, fungal culture and histopathological examination revealing aspergillus fumigatus and post op follow up with antifungal therapy.