The effect of sleep disorders on quality of life in patients with epilepsy: A multicenter study from Turkey.

Journal: Epilepsy & Behavior : E&B

Published: June 23, 2023

Abstract

Objective: We aimed to investigate sleep disorders in patients with epilepsy (PWE) and to investigate the effects of sleep disorders on quality of life.

Methods: In our multicenter study conducted in Turkey, 1358 PWE were evaluated. The demographic and clinical data of the patients were recorded. The Insomnia Severity Index (ISI), Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory (BDI), and Quality of Life in Epilepsy Inventory-10 (QOLIE-10) were administered.

Results: The mean age of 1358 patients was 35.92 ± 14.11 (range, 18-89) years. Seven hundred fifty-one (55.30 %) were women. Some 12.7 % of the patients had insomnia (ISI > 14), 9.6 % had excessive daytime sleepiness (ESS > 10), 46.5 % had poor sleep quality (PSQI > 5), and 354 patients (26.1 %) had depressive symptoms (BDI > 16). The mean QOLIE-10 score was 22.82 ± 8.14 (10-48). Resistant epilepsy was evaluated as the parameter with the highest risk affecting quality of life Adjusted odds ratio (AOR = 3.714; 95 % confidence interval (CI): [2.440-5.652] < 0.001)). ISI (AOR = 1.184; 95 % CI: [1.128-1.243]; p < 0.001), ESS (AOR = 1.081; 95 % CI: [1.034-1.130]; p < 0.001), PSQI (AOR = 0.928; 95 % CI: [0.867 - 0.994]; p = 0.034), BDI (AOR = 1.106; 95 % CI: [1.084-1.129]; p < 0.001), epilepsy duration (AOR = 1.023; 95 % CI: [1.004-1.041]; p = 0.014), were determined as factors affecting quality of life.

Conclusions: Sleep disorders are common in PWE and impair their quality of life. Quality of life can be improved by controlling the factors that may cause sleep disorders such as good seizure control, avoiding polypharmacy, and correcting the underlying mood disorders in patients with epilepsy.

Authors

Gönül Akdağ, Sibel Canbaz Kabay, Aylin Bican Demir, Ebru Ergin Bakar, Güray Koç, Sibel Üstün Özek, Ahmet Küçük, Miraç Ünsal, Abdurrahman Neyal, Miruna Florentina Ateş, Havva Çelik, Emine Kılıçparlar Cengiz, Gülnihal Kutlu, Dilek Ağırcan, Meltem Karacan Gölen, Semai Bek, Nilgün Çınar, Sevki Sahin, Aysel Şişman Bayar, Murat Terzi, Sude Kendirli Aslan, Safiye Kenar, Süleyman Kutluhan, Yasemin Ekmekyapar Fırat, Dilek Yılmaz Okuyan, Muhammet Bayar, Murat Mert Atmaca, Destina Yalçın, Fatma Genç, Leyla Köse Leba, Buket Yılmaz, Fettah Eren, Naci Bolu, Selda Keskin Güler, Tuba Akıncı, Aylin Reyhani, Neslişah Yıldırım Sitembölükbaşı, Nur Türkmen, Sibel Karşıdağ, Sibel Velioğlu, Ayşegül Demir, Barış Haytı, Buse Hasırcı Bayır, Firdevs Ezgi Uçan Tokuç, Göksemin Demir, Güngör Çakmakçı, Hülya Özkan, Onur Bulut, Özlem Kesim Şahin, Reyhan Sürmeli, Selma Tekin, Şerife Sarıoğlu, Tülin Gesoğlu Demir, Fatma Akkoyun Arıkan, Mustafa Çetiner

Relevant Conditions

Excessive Daytime Sleepiness, Epilepsy

The effect of sleep disorders on quality of life in patients with epilepsy: A multicenter study from Turkey.

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