The effect of the size of gold nanoparticle contrast agents on CT imaging of the gastrointestinal tract and inflammatory bowel disease.

Journal: BioRxiv : The Preprint Server For Biology
Published:
Abstract

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD). CT imaging with contrast agents is commonly used for visualizing the gastrointestinal (GI) tract in UC patients. CT is a common imaging modality for evaluating IBD, especially in patients with acute abdominal pain presenting to emergency departments. CT's major limitation lies in its lack of specificity for imaging UC, as the commonly used agents are not well-suited for inflamed areas. Recent studies gastrointestinal tract (GIT) in UC. Further systemic research is needed to explore novel contrast agents that can specifically image disease processes in this disease setting.

Authors
Derick Rosario Berríos, Amanda Pang, Leening Liu, Portia S Maidment, Johoon Kim, Seokyoung Yoon, Lenitza Nieves, Katherine Mossburg, Andrew Adezio, Peter Noel, Elizabeth Lennon, David Cormode