Neurotropic melanoma

Neurotropic melanoma is a variant of desmoplastic melanoma with a distinctive neural or Schwannian appearance of amelanotic spindled melanocytes. We report a 81 years old woman with a neurotropic melanoma on her left superciliary region. The lesion began as a lentigo maligna melanoma, Clark's level V, 4,08 mm. in thickness. The tumor relapsed on seven instances over a follow-up period of five years. Microscopic study showed a spindle cell pattern with marked neurotropism. Patient's general condition is good notwithstanding her evolution and relapses. This type of melanoma usually occurs on the face and, as we observed in our cases, exhibits a marked tendency for peripheral nerve invasion.