Functional Outcomes After Refractive Lens Exchange With Implantation of a Glistening-Free Diffractive Trifocal Intraocular Lens.

Objective: To evaluate visual outcomes and patient-reported results after bilateral femtosecond-laser-assisted refractive lens exchange (RLE) with the implantation of a diffractive trifocal intraocular lens.

Methods: Prospective interventional case series. Methods: A study of 27 patients (54 eyes) implanted with the Clareon PanOptix (Alcon) multifocal intraocular lens during femtosecond-laser-assisted RLE in a university hospital setting. The uncorrected (UDVA) and corrected (CDVA) distance visual acuity, uncorrected (UIVA) and distance-corrected (DCIVA) intermediate visual acuity at 60 cm, uncorrected (UNVA) and distance-corrected (DCNVA) near visual acuity at 40 and 33 cm were evaluated at 3 months postoperatively and compared with the preoperative values. In addition, we assessed the postoperative defocus curve, mesopic and photopic contrast sensitivity, and patient-reported spectacle independence.

Results: The mean postoperative binocular UDVA was -0.02 ± 0.06 logMAR and CDVA was -0.11 ± 0.05 logMAR. The UIVA was -0.07 ± 0.05 logMAR and DCIVA was -0.07 ± 0.07 logMAR. The UNVA at 40 cm was 0.03 ± 0.09 logMAR and DCNVA was -0.02 ± 0.06 logMAR; and, at 33 cm UNVA was 0.14 ± 0.10 logMAR and DCNVA was 0.11 ± 0.08 logMAR. In comparison to the preoperative binocular CDVA (-0.12 ± 0.08 logMAR), no statistically significant change was observed (P = 1.0), while all the other binocular visual acuities improved (P < .01). In the mean binocular defocus curve, the visual acuity was better than 0.10 logMAR in the range between +0.5 D and -3.0 D. The mean contrast sensitivity was within the normal range, and most patients reported complete spectacle independence.

Conclusions: The RLE surgery improved uncorrected visual acuity at far, intermediate, and near distances without negatively affecting the CDVA. Patients achieved a high level of spectacle independence.