Agreement between swept-source OCT and Scheimpflug biometers in ocular measurements.

Background: This study evaluated the agreement of the ocular parameters obtained with the two optical biometers, the IOLMaster 700 and the Galilei G6 Lens Professional.

Methods: A comparative prospective study was conducted on 159 eyes of 91 adult patients using the IOLMaster 700 and Galilei G6 devices by a single examiner. Agreement between ocular biometric parameters: white-to-white (WTW) distance, keratometry (flat (K1) and steep (K2), mean (Km)) of anterior, posterior, and total corneal surfaces, central corneal thickness (CCT), anterior chamber depth (ACD), and axial length (AL) were assessed using Bland-Altman analysis. Keratometry measurements were further transformed into power vector components J0 and J45 for astigmatism analysis. Clinically significant differences were defined as deviations in biometric parameters translating to differences of 0.25 D or more in refractive outcomes.

Results: Statistically and clinically significant difference was identified for ACD (mean difference: -0.15 mm), posterior corneal metrics: K1 (0.39 D), K2 (0.42 D), Km (0.41 D) and J0 (0.05 D) and total corneal metrics: K1 (0.95 D), K2 (0.91 D), Km (0.93 D) and J0 (0.13 D). No significant differences were found for J45 components of posterior and total K, WTW, CCT, and AL measurements.

Conclusions: The difference in measurements of anterior chamber depth (ACD), posterior K, and total K metrics are clinically significant making the two devices are clinically significant and not interchangeable. These variation in metrics can impact the refractive outcomes of refractive and cataract surgery with toric IOLs.