Appearance-related distress impacts psychological symptoms in Chinese patients with cleft lip.

This study aimed to explore the characteristics of appearance-related distress and the relationship between appearance-related distress, anxiety and depression symptoms in Chinese patients with cleft lip (CL). The Derriford Appearance Scale 59 (DAS-59), Generalized Anxiety Disorder-7 (GAD-7), and Patient Health Questionnaire-9 (PHQ-9) were used to screen for appearance-related distress, anxiety, and depression symptoms in Chinese patients with CL, respectively. A total of 63 patients with CL, comprising 43 unilateral and 20 bilateral cases, and 64 individuals without CL in the control group were included in the study. Appearance-related distress was compared between patients with CL and non-cleft individuals. The relationship between appearance-related distress and two psychological symptoms was estimated. The DAS-59 scores in patients with CL were significantly higher than those in non-cleft individuals. The DAS-59 scores in patients with CL who had anxiety or depression symptoms were significantly higher than those without symptoms, and the DAS-59 scores were correlated with GAD-7 and PHQ-9 scores. After adjustment for demographic variables, the DAS-59 scores were also positively associated with GAD-7 and PHQ-9 scores in patients with CL. More significant appearance-related distress was observed in Chinese patients with CL compared to the control group, but it did not exhibit a correlation with the patients' diagnosis (unilateral or bilateral), sex, age, or other demographic characteristics. Furthermore, appearance-related distress plays a significant role in psychological symptoms and may serve as a predictor of anxiety and depressive symptoms.