A 10-mm Monocusp Expanded Polytetrafluoroethylene Valved Conduit for Right Ventricular Outflow Tract Reconstruction in Neonates and Young Infants.

Journal: World Journal For Pediatric & Congenital Heart Surgery
Published:
Abstract

BackgroundCurrently, no ideal prosthesis is available for right ventricular outflow tract (RVOT) reconstruction in neonates and young infants. Therefore, we developed a 10-mm handmade monocusp expanded polytetrafluoroethylene (ePTFE) valved conduit and report our experience.MethodsA retrospective clinical review was conducted on 11 consecutive patients who underwent RVOT reconstruction with a 10-mm handmade monocusp ePTFE valved conduit since May 2018. Six patients underwent a definitive Rastelli operation, and five underwent palliative right ventricle-to-pulmonary artery conduit formation. The median age at the time of operation was 61 (range, 6-462; interquartile range [IQR]: 229) days, and the median weight was 4.0 (range, 3.0-11.6; IQR: 4.3) kg.ResultsOne patient died early due to brain hemorrhage, and one died late due to sepsis. The follow-up duration was 38.5 ± 18.9 months. The mean peak pressure gradients across the conduit were 6.5 ± 4.4 mm Hg at discharge and 22.0 ± 11.2 mm Hg at the latest follow-up echocardiography. Regarding conduit regurgitation, all conduits showed better than moderate grading at the last follow-up or before reintervention. There were seven conduit explantations and three catheter interventions for conduit-related reasons. The explantations included a definitive Rastelli operation in three patients and conduit stenosis due to somatic growth in four patients.ConclusionOur simple 10-mm handmade monocusp ePTFE valved conduit demonstrated satisfactory clinical outcomes and is be a suitable option for RVOT reconstruction in neonates and young infants.