Evaluating the Role of Gynecomastia Surgery in Improving Sexual Function and Hormonal Profiles.

Background: Patients with gynecomastia may experience hormonal imbalances and sexual dysfunctions such as erectile and ejaculatory disorders.

Objective: This study evaluates the changes in hormonal parameters and sexual function following gynecomastia surgery.

Methods: Thirty-two male patients (aged 15-65) without systemic or genetic comorbidities underwent gynecomastia surgery. Preoperative and postoperative hormonal parameters free and total testosterone, estrogen, prolactin, follicle-stimulating hormone [FSH], luteinizing hormone [LH], sex hormone-binding globulin [SHBG], and sexual function scores (International Index of Erectile Function [IIEF], Premature Ejaculation Diagnostic Tool [PEDT]) were assessed. A urologist blinded to the study evaluated patients andrologically.

Results: The mean age of the patients was 25.69 ± 10.37 years. Postoperative prolactin and estrogen levels significantly decreased (p=0.03 and p<0.001, respectively). All IIEF subscale scores showed significant postoperative improvements (p-values ranging from <0.001 to 0.006). PEDT scores significantly decreased postoperatively (p<0.001).

Conclusions: Surgical treatment of gynecomastia leads to significant improvements in hormonal parameters and sexual function. These benefits should be considered in surgical planning.