Improvements in Depressive Symptoms, Perceived Social Support, and Quality of Life Through an Educational Program in Community-Dwelling Older Adults With Frailty Phenotype: A Randomized Controlled Trial of the FRAGSALUD Project.

Background: This study examined the impact of an educational program on depressive symptoms, cognitive function, social support, quality of life, and physical frailty among community-dwelling older adults with frailty or prefrailty.

Methods: In this 12-month multicenter randomized controlled trial, 199 frail/prefrail community-dwelling older adults were allocated into the intervention (n = 109) or the control (n = 90) group. The 6-month educational intervention focused on guidelines for physical activity, nutrition, cognition, and psychosocial well-being, while participants in the control group maintained their usual healthcare attendance. Changes in depressive symptoms (15-item Geriatric-Depressive-Scale, GDS-15), cognitive function (Short Portable Mental Status Questionnaire, SPMSQ), social support (Duke-University of North Carolina Functional Social Support Questionnaire, Duke-UNC-11), quality of life (3-level EuroQoL five-dimensional questionnaire visual analog scale, EQ-VAS, and index, EQ-Index), physical frailty (Short Physical Performance Battery, SPPB, and Fried's criteria) were evaluated after six months of intervention and six months of follow-up.

Results: After the follow-up, the intervention group improved the GDS-15 score (p <0.001), Duke-UNC-11 score (p <0.001), quality of life (EQ-VAS: p = 0.001, EQ-Index: p = 0.010), SPPB score (p <0.001), and reduced Fried's criteria (p <0.001) compared to the control group, which worsened Duke-UNC-11 score (p = 0.012) and EQ-Index (p <0.001). No significant changes in cognitive function were observed. Lastly, all significant changes in study variables after follow-up were significantly correlated with each other (p <0.05), indicating an interrelated evolution.

Conclusions: This 6-month educational program improved depressive symptoms, social support, quality of life, and physical frailty in community-dwelling frail and prefrail older adults, as observed after a 6-month follow-up.