Inequities underlie the alarming resurgence of Tuberculosis as the world's top cause of death from an Infectious Disease - Breaking the silence and addressing the underlying root causes.

•The WHO End TB strategy is stalling as shown in the Global Tuberculosis Report 2023.•The main reason is unequal access to tuberculosis diagnosis and treatment.•Tuberculosis diagnosis and treatment must be expanded outside urban centers down to the smallest and most remote unit.•Screening risk populations for latent tuberculosis will help identify infected persons before they develop active tuberculosis.