Does Left Ventricular Rotational Mechanics Depend on Aortic Valve Annular Dimensions in Healthy Adults?-A Three-Dimensional Speckle-Tracking Echocardiography-Derived Analysis from the MAGYAR-Healthy Study.

Introduction. There is a balanced relationship between the left ventricle (LV), the aortic valve and the aorta, the functioning of which is essential for optimal circulation. Associations between simultaneously assessed LV rotational mechanics and aortic valve annular (AVA) dimensions respecting the cardiac cycle have never been assessed in clinical circumstances in healthy individuals by three-dimensional speckle-tracking echocardiography (3DSTE). The present study aimed to perform an extensive investigation in order to clarify their possible associations. Methods. The present study comprised 111 healthy individuals (mean age 35.3 ± 12.0 years, 69 males). Results. With increase in end-diastolic AVA area, tendentious increase in apical LV rotation and consequential LV twist could be detected. Basal and apical rotations and LV twist were tendentiously higher in case of mean end-systolic AVA area compared to lower/higher than mean end-systolic AVA area. With increase in basal LV rotation, tendentious decrease in end-diastolic AVA dimensions could be detected. End-systolic AVA dimensions were tendentiously smaller in case of mean basal LV rotation compared to lower/higher than mean basal LV rotations. With increase in apical LV rotation, tendentious increase in end-diastolic AVA dimensions could be detected. End-systolic AVA dimensions were tendentiously higher in case of mean apical LV rotation compared to lower/higher than mean apical LV rotations. Conclusions. No obvious significant association could be detected between simultaneously assessed LV rotational mechanics and AVA dimensions respecting the cardiac cycle in healthy adults.