Antifungal susceptibility of a collection of Aspergillus fumigatus strains isolated from patients with invasive pulmonary aspergillosis and COVID-19 associated aspergillosis.

We assessed the antifungal susceptibility of 86 Aspergillus fumigatus strains by a phenotypic test. Azole sensitivity was compared to a molecular test detecting cyp51A mutations. Azole resistance was quite limited, whereas strains from COVID-19 patients showed higher amphotericin B MICs. The molecular test showed a 100 %-agreement with the phenotypic assay.