Partial trisomy (10pter leads to 10q21) and partial monosomy (21pter leads to 21q21) due to a reciprocal balanced familial translocation (10;21)(q21;q21) (author's transl)

A newborn infant is reported with a karyotype showing a partial trisomy 10 (10pter leads to 10q21) and a partial monosomy 21 (21pter leads to 21q21) due to a reciprocal balanced familial translocation t(10;21)(q21;q21). This is the first case of partial trisomy 10 for the segment 10pter leads to 10q21.