Ammonia and amino acid metabolism y the portal-vein-drained viscera in chronic renal insufficiency.
Journal: Proceedings Of The European Dialysis And Transplant Association. European Dialysis And Transplant Association
Published:
Abstract
Arterial portal-venous differences (A-PV) of ammonia (NH3) and amino acids (AA) were measured in patients with chronic renal insufficiency (CRI) and in controls. In CRI, NH3 release by the portal-vein-drained viscera (PDV) is not different from controls, Gln uptake decreases, Glu extraction occurs, Pro and Thr output increases and Ser release becomes evident; one third of N released as NH3 and AA can be accounted for by Gln and Glu uptake. The N exchange across the PDV is similar in CRI and in controls.
Authors
A Tizianello, G De Ferrari, G Garibotto, G Chiggeri, C Robaudo, G Motta, M Nahum
Relevant Conditions