Malignant lymphomas of the intestinal tract. Histological and immunohistological findings in 22 intestinal lymphomas

The histology and immunohistology of 22 malignant lymphomas of the intestinal tract have been studied using the so-called "Kiel classification". We have found 12 lymphomas with low grade malignancy (lymphocytic, lympho-plasmocytoid, centrocytic, centroblastic-centrocytic) and 10 with high grade (centroblastic, lymphoblastic, immunoblastic). In all cases of lympho-plasmocytoid and immunoblastic lymphoma a monoclonal pattern of intracellular immunoglobulin was identified by the immunoperoxidae method. This technique offers considerable help in distinguishing between (monoclonal) malignant lymphomas and (polyclonal) lympho- or immunoproliferative processes.