The comparison of positive rates and clinical significance of 8 bronchodilator testing parameters sarcoidosis

Twenty asthmatic patients (with mild to severe attacks) were examined with bronchodilator test. Eight parameters, FVC, FEV1, PEF, FEF25-75%, FEF25-75% after inhaling bronchodilator (FEF25-75% Iso), thoracic gas volume (Vtg), airway resistance (Raw) and specific conductance (SGaw), were investigated, compared and analysed. The results showed that the positive rate (PR) of FEV1, the most commonly used parameter at present, was only 70%; the PR of two new parameters FEF 25-75% Iso and SGaw were 95% respectively, the change rate (%) of FEV1 was significantly related to that of many other parameters. The pathophysiology and clinical significance of each parameter were discussed.