Effects of space flight factors on production of oxygen radicals by phagocytes in cosmonauts

In cosmonauts participated in space missions of various duration there changed one of the most important functions of phagocytes--the capacity to produce the active forms of oxygen during effect of corpuscular activator of zymosan. These changes depending on flight duration and individual peculiarities of cosmonauts manifested both as increase and decrease of the parameters studied. Family analysis of chemiluminescence of phagocytosing cells of the blood has revealed much importance of genotype in genesis of the variability of this function which points to the utility of an individual approach to evaluation of the immunity in cosmonauts.