1,4-pentadienyl-3-sulfonamides: frameworks for "disfavored" radical cascade cyclizations.

Journal: Organic Letters
Published:
Abstract

[reaction: see text]. 1,4-pentadienyl-3-sulfonamides afford products including those resulting from disfavored 5-endo-trig reactions when subjected to radical cyclization conditions. Products resulting from pathways featuring 4-exo-trig cyclizations are also detected, even when the 4-exo-trig reaction leads to a highly strained bicyclo[3.2.0] ring system.

Authors
S Bommezijn, C Martin, A Kennedy, D Lizos, J Murphy