Kearns-Sayre syndrome with GH deficiency

A case of Kearns-Sayre syndrome with failure to thrive, cytochrome oxidase deficiency in muscle fibers, mtDNA deletion and deficient GH responses to stimulation tests is reported. The patient, when 9 years old, was treated with GH without significant improvement in growth velocity. The opportunity of search for GH deficiency in children with Kearns-Sayre syndrome and failure to thrive is stressed.