Lipid peroxidation and antioxidant system parameters in lacrimal fluid in post-traumatic uveitis

Lipid peroxidation (LPO) values and activities of antioxidant enzymes, catalase, and superoxide dismutase were studied in the lacrimal fluid (LF) of the damaged and intact eyes of 87 patients with posttraumatic uveitis (PTU). Catalase activity was decreased in sluggish PTU and increased in exacerbation, which is attributed to decompensation of the antioxidant system and its effect on the course of posttraumatic inflammation. Similar changes were detected in LF of paired eyes. Long treatment with antioxidants is recommended; the authors consider that analysis of the paired eye LF cannot be used for control in patients with PTU.