Successful pregnancy in a gonadectomized woman with 46,XY gonadal dysgenesis and gonadoblastoma.

Objective: To present a case of successful pregnancy after conservative bilateral gonadectomy without adjuvant chemotherapy and radiotherapy in a 46,XY gonadal dysgenetic woman with gonadoblastoma and malignant germ cell tumor.

Methods: Case report. Methods: Infertility center in university hospital. Methods: An 18-year-old female with 46,XY karyotype underwent bilateral gonadectomy, and the pathology revealed gonadoblastoma with malignant mixed germ cell tumor. Methods: Chromosomal analysis, bilateral gonadectomy, donor oocyte, and IVF program. Methods: Tumor markers and pregnancy result.

Results: The patient was free from tumor recurrence after 13 years' follow-up. A successful twin pregnancy was achieved after oocyte donation and IVF.

Conclusions: Gonadectomy without adjuvant therapies could be done in 46,XY gonadal dysgenetic women with gonadoblastoma in view of preservation of future fertility.