Comparative research of the donor site wound healing in occlusive and dry environments

Objective: To compare and research the process of wound healing in occlusive moist environment and dry environment on the skin donor site.

Methods: The wound healing of adult skin donor site was studied by clinical observation, histological and electromicroscopical examinations on the operative day and the 1st, 2nd, 3rd, 4th, 7th days postoperatively, each skin donor site was divided into two parts: occlusive environment and dry environment.

Results: The wounds of occlusive moist environment healed faster than those of dry environment; the fibroblasts were more active and activated earlier, revascularization and re-epithelialization happened earlier and more quickly.

Conclusions: In occlusive environment, more active fibroblasts can accelerate granulation growth; quicker regenerative capillaries bring more nourishment; quicker re-epithelialization accelerates the wound healing.