Solitary fibrous tumor (SFT) of the nasal mucosa

Methods: A case of a 76-year-old-man is reported who was referred to the department because of an increasing tumor of the right nasal cavity. After surgical treatment of the neoplasm histological examination revealed a solitary fibrous tumor (SFT) of the nasal mucosa.

Conclusions: Solitary fibrous tumors mostly occur as pleural neoplasms. Extrapleural locations of this mesenchymal tumor species are rarely found in the head and neck region. These extrapleural tumors are sometimes difficult to diagnose because of their histologic variability. Solitary fibrous tumors typically show intense staining for CD 34, vimentin, bcl-2 and sometimes for desmin. These immunohistochemical features have made differentiation from other lesions in the head and neck region much easier. Most pleural and extrapleural solitary fibrous tumors behave in a benign fashion with good prognosis, though aggressive lesions with local invasion or distant metastases have been reported. Definitive surgical treatment with complete tumor removal is recommended in literature. Encouraging chemotherapy or radiotherapy results have not been reported so far.