Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma (FREYA)
Status: Recruiting
Location: See location...
Intervention Type: Other, Dietary supplement
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The overall aim of the study is to develop a nutritional preventive fish oil supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that both supplementations in higher doses than recommended could reduce the risk of disease development.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:
• Pregnant Danish women before week 26 with blood levels of EPA+DHA below 4.7% of total fatty acids
• No planned use of fish oil supplementations
• No endocrine-, heart-, kidney- or auto-immune disorders
Locations
Other Locations
Denmark
Copenhagen University Hospital of Copenhagen
RECRUITING
Gentofte
Contact Information
Primary
Klaus Bønnelykke, PhD
kb@copsac.com
+45 38677360
Backup
Ulrik Ralfkiaer, PhD
administration@dbac.dk
+45 38674164
Time Frame
Start Date: 2024-12-20
Estimated Completion Date: 2033-03
Participants
Target number of participants: 2000
Treatments
Experimental: n-3 fatty acid of 2.4 g per day
Oral intake of 4 capsules daily from week 22-26 of gestation until 1 week after delivery
Placebo_comparator: Rape seed oil
Oral intake of 4 capsules daily from week 22-26 of gestation until 1 week after delivery
Related Therapeutic Areas
Sponsors
Leads: Professor Klaus Bønnelykke