Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA): A Randomized Control

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Other, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting. The purpose of this study is to determine the feasibility of implementing this treatment in community care centers.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 7
Maximum Age: 17
Healthy Volunteers: f
View:

• The adolescent is between the ages of 7 to 17 upon enrollment with an established autism spectrum disorder diagnosis (ASD) made by a standardized assessment (e.g., Autism Diagnostic Observation Schedule-Second Edition; Childhood Autism Rating Scale-Second Edition), confirmed by the Social Communication Questionnaire (SCQ) ≥ 11 and/or total score ≥ 7 on the Autism Diagnostic Observation Schedule-2 (ADOS-2). Dr. Storch will review diagnostic reports to determine whether an appropriate ASD diagnosis has been established.

• The adolescent has clinically elevated symptoms of anxiety based on elevated scores on the Pediatric Anxiety Rating Scale modified for Autism Spectrum Disorder (\>12).

• Anxiety is the primary concern and the child is appropriate for intervention focus, as determined by completion of a structured psychiatric diagnostic interview (the Mini International Neuropsychiatric Interview) by an independent evaluator (IE) supervised by an experienced, licensed psychologist determines that the child is appropriate for the intervention focus.

• Child has a verbal intelligence quotient greater than or equal to 70, as measured by the Verbal Comprehension Index of the Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V).

• One parent/guardian is able and willing to participate (i.e., available during therapy sessions, attend study assessments).

• Child is eligible to receive services at the participating clinic.

• Both parent and child can read and/or understand English and/or Spanish.

• Both parent and child reside in Texas or Pennsylvania.

Locations
United States
Maryland
Johns Hopkins University
ACTIVE_NOT_RECRUITING
Baltimore
Pennsylvania
Hospital of the University of Pennsylvania
ACTIVE_NOT_RECRUITING
Philadelphia
Texas
Baylor College of Medicine
RECRUITING
Houston
Contact Information
Primary
Eric Storch, PhD
eric.storch@bcm.edu
713-798-3579
Time Frame
Start Date: 2024-02-16
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 60
Treatments
Active_comparator: Cognitive Behavioral Therapy
Participants will receive cognitive behavioral therapy that has been adapted for autistic youth with anxiety. These sessions will also include components of exposure. Participants will receive therapy around once a week for 14 weeks.
Placebo_comparator: Treatment as Usual
Participants will complete treatment as usual. They will be referred to other community resources, including skills training. Additionally, participants may begin or end therapy and/or medication.
Related Therapeutic Areas
Sponsors
Collaborators: Johns Hopkins University, University of Pennsylvania
Leads: Baylor College of Medicine

This content was sourced from clinicaltrials.gov