This paper reports a female patient with. Turner's syndrome and a giant aneurysm of the ascending aorta with pronounced aortic insufficiency in the presence of the bicuspid aortic valve, type II aortic dissection that occurred after two operations: resection of aortic coarctation with end-to-end anstomosis, recoarctation syndrome and aortic ascenoing-descending bypass grafting via the right-sided thoracotomy. The patient underwent prosthetics of the ascending aorta and aortic valve with ascending-descending repeated bypass grafting under conditions of complete peripheral cardiopulmonary bypass, hypothermia (22 degrees C) antegrade brain perfusion via the right subclavian artery.