Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Croup (laryngotracheobronchitis) is a viral infection of the upper airway that causes throat swelling, leading to a barking cough, stridor, and hoarseness. It mainly affects children aged 6 months to 12 years, peaking at around 2 years. Most cases are mild and self-limiting. Emergency treatments include cool mist, nebulized epinephrine, and steroids. Steroid therapy, particularly dexamethasone (oral or intramuscular), is commonly used, with recent studies suggesting intramuscular dexamethasone may be more effective. However, most research has focused on hospitalized patients, and there is a lack of local data for mild cases. This study aims to address that gap and improve patient counseling and future research

Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 12
Healthy Volunteers: f
View:

• Patient age 2 to 12 years

• Both genders

• Diagnosed with croup as operational definitions

Locations
Other Locations
Pakistan
Khyber Teaching Hospital
RECRUITING
Peshawar
Contact Information
Primary
Sadiq Akbar, MBBS
sadiqakbar77@yahoo.com
+92 344 9888158
Time Frame
Start Date: 2024-06-01
Estimated Completion Date: 2025-07-01
Participants
Target number of participants: 192
Treatments
Active_comparator: Group A (oral dexamethasone )
Patients in group A will receive oral dexamethasone which will be administered at 0.6mg/kg as single dose
Active_comparator: Group B (intramuscular dexamethasone )
Patients in group B will receive intramuscular dexamethasone which will be administered in 0.6mg/kg strength as intra-gluteal injection as single dose
Related Therapeutic Areas
Sponsors
Leads: Arooj Khan

This content was sourced from clinicaltrials.gov