Objective: To establish the efficacy and safety of nonpenetrating deep sclerectomy versus trabeculectomy in primary open-angle glaucoma.

Methods: Prospective randomized trial. Methods: Thirty-nine patients (78 eyes) with bilateral primary open angle glaucoma were included in the study. Methods: Eyes were randomly assigned to receive deep sclerectomy in one eye and trabeculectomy in the other eye. Methods: Mean intraocular pressure (IOP), postoperative medications, visual acuity, success rate, and complications.

Results: At 12 months, mean IOP reduction was 12.3 +/- 4.2 (sclerectomy) versus 14.1 +/- 6.4 mmHg (trabeculectomy) (P = 0.15), and an IOP

Conclusions: Deep sclerectomy may provide comparable IOP reduction with fewer complications in management of primary open angle glaucoma.