Transurethral resection of prostate (TURP) is a rare but extremely dangerous condition. Although this complication is well described previously, we still see it those days.

Methods: We report a case of 66-year-old male patient presented with symptoms of enlarged prostate. Ultrasound showed the prostate weight was 90 g. He was scheduled for transurethral resection of prostate. The procedure took 65 min with the use of monopolar device. One hour after operation, he had confusion, bradycardia, and elevated blood pressure. Laboratories showed hyponatremia and hyperkalemia. We infused the patient with saline 3% solution after the diagnosis of TURP syndrome. On next day, he gained his full recovery and we discharged him. Our patient suffered from TURP syndrome. Laboratory evaluation of blood electrolytes led to confirm the diagnosis. We immediately infused hypertonic saline intravenously. We monitored the patient clinically and with serial assessments of blood electrolytes.

Conclusions: TURP syndrome is considered a serious complication in urology surgery. Urologists should suspect this complication in prolonged TURP surgery. Early diagnosis is crucial to save patient's life.