Meckel's diverticulum (MD) is the most common small intestine anomaly. Although it is often asymptomatic, in pediatric patients it typically presents as obstruction or lower gastrointestinal bleeding due to ileo-ileal intussusception. We present the case of a pediatric patient in his second decade of life with symptoms of an acute abdomen and laboratory abnormalities suggesting an infectious or inflammatory process. A computed tomography scan revealed small bowel dilation, increased bowel wall diameter, and air-fluid levels. He underwent exploratory laparotomy, which revealed an intussusception of a MD. The affected segment was resected, followed by an end-to-end anastomosis. In cases where complications of MD are strongly suspected, the surgeon should opt for surgical management as soon as possible, whether by laparotomy, laparoscopy, or laparoscopically assisted surgery. Regardless of the available options, an appropriate decision should be made based on intraoperative findings and potential postoperative complications. Surgical treatment should depend on intraoperative findings and the surgeon's expertise to ensure a safe and complication-free procedure.