The treatment of multiple sclerosis (MS) has been remarkably progressed, especially in disease modifying therapies (DMTs). Recently, fingolimod, a novel oral DMT, was added to treatment options for relapsing-remitting MS (RRMS) in Japan. In Western countries, more kinds of DMTs are available for treatment for RRMS. Further, clinical trials on many drugs including DMTs are on-going, and the arrival of multiple options for MS is promising. This article reviews the recent progress in current therapeutic strategies for MS and the potential options for future MS treatments.