Objective: Laparoscopy is a safe, feasible technique for benign pancreatic pathologies and has been increasingly reported for neuroendocrine tumors located at the body and tail of the pancreas. We report a case of successful enucleation of a nonfunctioning neuroendocrine tumor located at the head of the pancreas, in a patient with multiple endocrine neoplasia type I.

Methods: A 5-cm nonfunctioning neuroendocrine tumor at the pancreatic head was identified by computerized tomography scan. Laparoscopic ultrasound did not reveal additional tumors on any other part of the pancreas.

Results: Enucleation was successfully performed for this solitary tumor because of its favorable position. Histology revealed an islet cell tumor. No postoperative complications occurred and recovery was rapid.

Conclusions: Laparoscopic enucleation of neuroendocrine tumor at the pancreatic head is safe and feasible for select patients.