Optic Nerve Head Strain as Biomarker for Glaucoma

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The investigators will test the hypothesis that images of the optic nerve head taken a 2 different eye pressures will yield strain estimates that are predictive of the course of glaucoma.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: t
View:

• Existing glaucoma patients of Johns Hopkins

Locations
United States
Maryland
Johns Hopkins University
RECRUITING
Baltimore
Contact Information
Primary
Harry A Quigley
hquigley@jhmi.edu
4109556051
Time Frame
Start Date: 2024-07-01
Estimated Completion Date: 2028-01-31
Participants
Target number of participants: 130
Treatments
Other: All subjects
Each subject will be imaged at two different times and eye pressures
Related Therapeutic Areas
Ocular Hypertension (OHT)
Glaucoma
Pigment-Dispersion Syndrome
Sponsors
Collaborators: National Eye Institute (NEI)
Leads: Johns Hopkins University

This content was sourced from clinicaltrials.gov

Similar Clinical Trials

Treating Psychosocial Distress in Glaucoma

Treating Psychosocial Distress in Glaucoma

Enrollment Status: Recruiting
Publish Date: June 05, 2025
Intervention Type: Behavioral
Study Phase: Not Applicable

A Phase III Study Including a Single-Arm, Open-Label, Multi-Dose PK Study Cohort and a Randomized, Evaluator-Masked, Active Drug Controlled, Parallel Group, Multicenter, Bridging Study Cohort With a Long-term Follow-up Phase Assessing the Efficacy and Safety of DE-117B Eye Drops in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China

A Phase III Study Including a Single-Arm, Open-Label, Multi-Dose PK Study Cohort and a Randomized, Evaluator-Masked, Active Drug Controlled, Parallel Group, Multicenter, Bridging Study Cohort With a Long-term Follow-up Phase Assessing the Efficacy and Safety of DE-117B Eye Drops in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China

Enrollment Status: Recruiting
Publish Date: February 28, 2025
Intervention Type: Drug
Study Phase: Phase 3

A Prospective, Multicenter Clinical Study to Evaluate the Safety and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Subjects With Glaucoma

A Prospective, Multicenter Clinical Study to Evaluate the Safety and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Subjects With Glaucoma

Enrollment Status: Recruiting
Publish Date: May 23, 2025
Intervention Type: Device
Study Phase: Phase 3
View All