Asthma is a condition characterized by ongoing inflammation of the lower respiratory system, leading to symptoms such as shortness of breath, wheezing, coughing, and chest tightness. Beyond acute symptoms, children with asthma may face ongoing issues, such as decreased physical fitness, sleep disturbances, and a reduced quality of life. This study aimed to explore the connections between sleep quality, asthma control, pulmonary inflammation, exercise capacity, and overall wellbeing in children aged 6 to 12 years. Forty children with varying asthma severity were evaluated for clinical control status, sleep disturbances, quality of life, and exercise ability using various questionnaires and tests. Results showed that 15% had intermittent/mild asthma while 85% had moderate/severe asthma, with 75% experiencing uncontrolled asthma. The analysis indicated a strong correlation between improved asthma control, reduced pulmonary inflammation, better sleep quality, and enhanced quality of life, accounting for 20% of the variations in the children's quality of life scores.