Subcutaneous panniculitis such as T-cell lymphoma (SPTCL) is a very rare disorder. Patients usually present with multiple subcutaneous nodules on the extremities without visceral disease. Dissemination to extra-cutaneous sites is unusual. Only a few cases of SPTCL have been reported in the literature describing the findings of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET). Here, we represent an interesting and unusual case of diffuse SPTCL with snow Leopard skin appearance on 18F-FDG PET/computed tomography.