Virilizing adrenal ganglioneuroma : A rare differential diagnosis in testosterone secreting adrenal tumours
Journal: Der Pathologe
Published:
Abstract
Testosterone secreting tumours of the adrenal glands are usually adrenal carcinomas or adenomas. Here we report the rare case of an adrenal ganglioneuroma with ectopic Leydig cells, a so-called virilizing adrenal ganglioneuroma. Clinically it is characterized by symptoms of virilization, histologically by the occurrence of a population of eosinophilic cells. In the absence of crystalloids of Reinke this cell population can be identified as Leydig cells based on positive immunohistochemical staining of inhibin and calretinin.
Authors
N Gaisa, G Klöppel, B Brehmer, J Neulen, P Stephan, R Knüchel, A Donner
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