Coding of Speech Signals in the Human Auditory Nerve - an Exploratory Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The fine evaluation of the function of auditory neurons in silence and in noise in humans is difficult, if not impossible, to date with the conventional methods available. That is why in certain situations, the hearing aids of patient with hearing loss fail, especially in the presence of noise. In this study the investigators aim at investigating the global spontaneous and sound evoked human auditory nerve activity from electrophysiological acquisitions performed directly on the cochlear nerve in patients requiring posterior fossa surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Will be included as hearing impaired patients:

• male or female

• over 18 years of age

• who are to undergo surgery on the cerebellopontine angle (microvascular decompression, vestibular neurotomy, removal of a meningioma or schwannoma tumor)

• with a mild to severe sensorineural hearing loss defined by an average hearing loss (average of thresholds obtained at 500, 1000, 2000 and 4000 Hz) greater than 20 dB and less than 90 dB in pure tone bone conduction audiometry on the side of the operated ear.

• affiliated to a social security system.

• have read the information note describing the study and have agreed in writing to participate by signing the informed consent form.

⁃ Will be included as normal hearing patients:

• male or female

• over 18 years of age

• who are to undergo surgery in the cerebellopontine angle (microvascular decompression, vestibular neurotomy, removal of a meningioma or schwannoma tumor)

• free of neuro-sensory deafness, defined by average hearing thresholds less than or equal to 20 dB in tonal bone conduction audiometry on the side of the operated ear

• affiliated with a social security system.

• having read the information note describing the study and having agreed in writing to participate by signing the informed consent form.

Locations
Other Locations
France
Damien JOLLY
RECRUITING
Reims
Contact Information
Primary
Xavier DUBERNARD
xdubernard@chu-reims.fr
03.26.78.68.92
Time Frame
Start Date: 2021-12-07
Estimated Completion Date: 2027-06-07
Participants
Target number of participants: 60
Treatments
Active_comparator: Subjects with no hearing loss
Experimental: subjects with hearing loss
Sponsors
Leads: CHU de Reims

This content was sourced from clinicaltrials.gov