• Newly diagnosed exocrine pancreatic cancer with either pathology, histology, or radiology imaging documented as adenocarcinoma

• Patient is a candidate for surgical resection of pancreatic cancer

• ≥ 18 years old at the time of informed consent

• ECOG Performance Status 0-2

• Patients with or without neoadjuvant chemotherapy will be eligible

• Ability to provide written informed consent and HIPAA authorization

• Women of childbearing potential definition must have a negative pregnancy test within 14 days of registration. All women (regardless of sexual orientation, having undergone a tubal ligation, or remaining celibate by choice) are considered to have childbearing potential unless they meet one of the following criteria:

• Prior hysterectomy or bilateral oophorectomy;

• Has not had menses at any time in the preceding 24 consecutive months

• Candidate for surgery per standard of care of per surgeon's discretion