Incidence and Clinical Impact of Serum Hyperamylasemia (POH) After Pancreatectomy on Postoperative Outcome and Patient Safety

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Recent evidence suggests that postoperative hyperamylasemia (POH) is a predictor of morbidity after pancreatectomy. This is based on the assumption that pancreatitis after pancreatectomy (PPAP) is a major trigger for the development of complications and is indicated by hyperamylasemia. Standardized prospective analysis and correlation with other laboratory parameters, hasn't been performed to date. Therefore the overall study aims are: * To prospectively evaluate the incidence and assess the clinical value of biochemical changes for the postoperative course. * To confirm and improve the definition and classification of postpancreatectomy acute pancreatitis (PPAP) of the International Study Group of Pancreatic Surgery (ISGPS) and to provide knowledge for effective early management of complications.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• All patients undergoing pancreatic resection for malignant and benign disease with or without pancreatic anastomosis

• Patients aged 18-85 years

• Willingness to participate as demonstrated by giving a written informed consent.

Locations
Other Locations
Germany
University Hospital Dresden, Dept. Visceral, Thoracic and Vascular Surgery
RECRUITING
Dresden
Contact Information
Primary
Olga Radulova-Mauersberger, Dr. med.
studienzentrum-vtg@ukdd.de
+49 351 458-0
Time Frame
Start Date: 2023-07-18
Estimated Completion Date: 2026-04
Participants
Target number of participants: 150
Sponsors
Leads: Technische Universität Dresden

This content was sourced from clinicaltrials.gov