Methods: Anterior single- and dual-rod instrumented human and ovine thoracolumbar spines, with and without structural interbody support (SIS), were biomechanically tested and compared in flexion, lateral bending, and torsion. Objective: To determine significant differences in global stiffness of the constructs in an attempt to clarify specific indications for each in the treatment of spinal deformities.

Background: Single- and dual-rod anterior systems have been used without any consensus as to indications for one versus the other. The potential added benefit of incorporating SIS and transverse connectors (dual-rod) with these constructs has also not been fully explored.

Methods: Four human cadaveric and six ovine spines were instrumented in single- and dual-rod constructs and biomechanically tested intact, postdiscectomy with and without SIS, with single- and dual-rod constructs, and with and without transverse connectors (ovine only). Biomechanical testing modes were flexion, lateral bending, and torsion.

Results: In the human cadaveric specimens, testing in flexion revealed that SIS was the major contributing factor for construct stiffness. In lateral bending, stiffness of single- and dual-rod constructs with and without SIS was equivalent. In torsion, both single- and dual-rod instrumentation and SIS appeared to contribute to global stiffness. In ovine specimens, dual rods were stiffer than single-rod constructs and SIS played only a minor role. Transverse connectors appeared to significantly stiffen dual-rod constructs in torsion only.

Conclusions: Dual-rod constructs with SIS appear to be the best combination for providing stiffness in anterior instrumentation. The addition of cross-links to anterior constructs does not appear to increase stiffness except in torsion.