Studies on chemical constituents from flowers of Chrysanthemum indicum

Objective: To study the chemical constituents of the flowers of Chrysanthemum indicum.

Methods: Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physico-chemical and spectral data.

Results: From the 80% ethanol extract of the material, seven compounds were isolated. Their structures were identified as acacetin(1), acacetin-7-O-(6"-O-acetyl) beta-D-glucopyranoside (2), linarin (3), apigenin-7-O-beta-D-glucopyranoside(4), chlorogenic acid (5), vanillic acid(6) and sucrose(7), respectively.

Conclusions: Compounds 2, 4, 6 and 7 are isolated from C. indicum for the first time.