Studies on chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium)

Objective: To study the chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium).

Methods: The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences.

Results: Eleven compounds were obtained and identified as luteolin (1), quercetin (2), acacetin 7-O-beta-D-(3"-acetyl) -glucopyranoside (3), luteolin 7-O-beta-D-(6"-acetyl)-glucopyranoside (4), hesperetin 7-O-beta-D-glucopyranoside (5), acacetin 7-O-beta-D-glucopyranoside (6), diosmetin 7-O-beta-D-glucopyranoside (7), apigenin 7-O-beta-D-glucopyranoside (8), hesperidin (9), linarin (10), and luteolin 7-O-beta-D-glucopyranoside (11).

Conclusions: Compounds 4, 5 were isolated from the plant for the first time.