Learn About Allergic Conjunctivitis

What is the definition of Allergic Conjunctivitis?

The conjunctiva is a clear layer of tissue lining the eyelids and covering the white of the eye. Allergic conjunctivitis occurs when the conjunctiva becomes swollen or inflamed due to a reaction to pollen, dust mites, pet dander, mold, or other allergy-causing substances.

What are the alternative names for Allergic Conjunctivitis?

Conjunctivitis - allergic seasonal/perennial; Atopic keratoconjunctivitis; Pink eye - allergic

What are the causes of Allergic Conjunctivitis?

When your eyes are exposed to allergens (which cause allergies), a substance called histamine is released by your body. The blood vessels in the conjunctiva become swollen. The eyes can become red, itchy, and teary very quickly.

The pollens that cause symptoms vary from person to person and from area to area. Tiny pollens that may cause allergic symptoms include grasses, ragweed and trees. These same pollens may also cause hay fever.

Your symptoms may be worse when there is more pollen in the air. Higher levels of pollen are more likely on hot, dry, windy days. On cool, damp, rainy days most pollen is washed to the ground.

Mold, animal dander, or dust mites may cause this problem also.

Allergies tend to run in families. It is hard to know exactly how many people have allergies. Many conditions are often lumped under the term "allergy" even when they might not truly be an allergy.

What are the symptoms of Allergic Conjunctivitis?

Symptoms may be seasonal and can include:

  • Intense itching or burning eyes
  • Puffy eyelids, most often in the morning
  • Red eyes
  • Stringy eye discharge
  • Tearing (watery eyes)
  • Widened blood vessels in the clear tissue covering the white of the eye
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What are the current treatments for Allergic Conjunctivitis?

The best treatment is to avoid what causes your allergy symptoms as much as possible. Common triggers to avoid include dust, mold and pollen.

Some things you can do to ease symptoms are:

  • Use lubricating eye drops.
  • Apply cool compresses to the eyes.
  • Do not smoke and avoid secondhand smoke.
  • Take over-the-counter oral antihistamines or antihistamine or decongestant eye drops. These medicines can offer more relief, but they can sometimes make your eyes dry. Do not use the eye drops if you have contact lenses in place. Also, do not use the decongestant eye drops for more than 5 days, as rebound congestion can occur.

If home-care does not help, you may need to see a provider for treatments such as eye drops that contain antihistamines or eye drops that reduce swelling.

Mild steroid eye drops can be prescribed for more severe reactions. You may also use eye drops that prevent a type of white blood cell called mast cells from causing swelling. These drops are given along with antihistamines. These medicines work best if you take them before you come in contact with the allergen. Referral to an ophthalmologist before using steroid eye drops should be done since intraocular pressure measurements and a more thorough eye exam (using a slit lamp) is needed.

Who are the top Allergic Conjunctivitis Local Doctors?
Elite in Allergic Conjunctivitis
Elite in Allergic Conjunctivitis
Padova, IT 

Andrea Leonardi practices in Padova, Italy. Ms. Leonardi and is rated as an Elite expert by MediFind in the treatment of Allergic Conjunctivitis. Her top areas of expertise are Giant Papillary Conjunctivitis, Allergic Conjunctivitis, Vernal Keratoconjunctivitis, and Conjunctivitis (Pink Eye).

Elite in Allergic Conjunctivitis
Elite in Allergic Conjunctivitis
Chiba, JP 

Nobuyuki Ebihara practices in Chiba, Japan. Mr. Ebihara and is rated as an Elite expert by MediFind in the treatment of Allergic Conjunctivitis. His top areas of expertise are Giant Papillary Conjunctivitis, Allergic Conjunctivitis, Vernal Keratoconjunctivitis, Vitrectomy, and Trabeculectomy.

 
 
 
 
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Elite in Allergic Conjunctivitis
Elite in Allergic Conjunctivitis
Tokyo, JP 

Akira Matsuda practices in Tokyo, Japan. Matsuda and is rated as an Elite expert by MediFind in the treatment of Allergic Conjunctivitis. Their top areas of expertise are Giant Papillary Conjunctivitis, Allergic Conjunctivitis, Vernal Keratoconjunctivitis, Trabeculectomy, and Vitrectomy.

What is the outlook (prognosis) for Allergic Conjunctivitis?

Symptoms often go away with treatment. However, they can persist if you continue to be exposed to the allergen.

Long-term swelling of the outer lining of the eyes may occur in those with chronic allergies or asthma. It is called vernal conjunctivitis. It is most common in young males, and most often occurs during the spring and summer.

What are the possible complications of Allergic Conjunctivitis?

In severe cases of allergic conjunctivitis, there could be more severe inflammation. This can, rarely, affect your vision.

When should I contact a medical professional for Allergic Conjunctivitis?

Contact your provider if:

  • You have symptoms of allergic conjunctivitis that do not respond to self-care steps and over-the-counter treatment.
  • Your vision is affected.
  • You develop eye pain that is severe or becoming worse.
  • Your eyelids or the skin around your eyes becomes swollen or red.
  • You have a headache in addition to your other symptoms.
What are the latest Allergic Conjunctivitis Clinical Trials?
Contribution of Local Nasal IgE Production to the Boost of Systemic Allergen-specific IgE Production Upon Nasal Allergen Contact - an Explorative Pilot Study

Summary: IgE-associated allergies are consistently on the rise forming an enormous wellbeing concern and affecting about 25% of the population around the world, with main prevalence in developed nations. Birch pollen is one important allergen driving allergic conjunctivitis and rhinitis. The characteristics and location IgE producing cells in the nose and their contribution to the subsequent increase in al...

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A Single-Center, Randomized, Double-masked, Vehicle-controlled Phase 2 Study Evaluating the Safety and Efficacy of TL-925 Ophthalmic Emulsion 0.1% Compared to Vehicle for the Treatment of Allergic Conjunctivitis in the Conjunctival Allergen Challenge (Ora-CAC®) Model

Summary: In this prospective, Phase 2, randomized, double-masked, vehicle controlled study, approximately 66 eligible subjects will be randomized 1:1 to receive either TL-925 or placebo as topical ophthalmic eye drops administered bilaterally. The study comprises of a screening and treatment period using the conjunctival allergen challenge model to evaluate TL-925 for the treatment of allergic conjunctivit...

Who are the sources who wrote this article ?

Published Date: July 22, 2024
Published By: Deborah Pedersen, MD, MS, Allergy & Asthma Care, PC, Taunton, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Cioffi GA, Liebmann JM. Diseases of the visual system. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 391.

Rubenstein JB, Patel P. Allergic conjunctivitis. In: Yanoff M, Duker JS, eds. Ophthalmology. 6th ed. Philadelphia, PA: Elsevier; 2023:chap 4.7.