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          Last Updated: 06/27/2025

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          3 clinical trials found

            A Randomized Phase II Study of CHO(E)P vs CC-486-CHO(E)P vs Duvelisib-CHO(E)P in Previously Untreated CD30 Negative Peripheral T-Cell Lymphomas

            A Randomized Phase II Study of CHO(E)P vs CC-486-CHO(E)P vs Duvelisib-CHO(E)P in Previously Untreated CD30 Negative Peripheral T-Cell Lymphomas

            Who is this study for: Patients with Lymphoma
            Enrollment Status: Recruiting
            Publish Date: April 02, 2025
            Intervention Type: Drug
            Study Drugs: Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, Etoposide, Duvelisib, Oral Azacitidine
            Study Phase: Phase 2

            Summary: This phase II trial studies the effect of duvelisib or CC-486 and usual chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone in treating patients with peripheral T-cell lymphoma. Duvelisib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as CC-486, cyclophosphamide, doxorubicin, vincrist...

            A Phase 1a/1b Trial in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma to Determine the Safety Profile, Pharmacology, and Maximum Tolerated Dose of ST-001, a Fenretinide Phospholipid Suspension (12.5 mg/mL) for Intravenous Infusion

            A Phase 1a/1b Trial in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma to Determine the Safety Profile, Pharmacology, and Maximum Tolerated Dose of ST-001, a Fenretinide Phospholipid Suspension (12.5 mg/mL) for Intravenous Infusion

            Who is this study for: Patients with relapsed/refractory T-cell non-Hodgkin's lymphoma
            Enrollment Status: Recruiting
            Publish Date: March 26, 2025
            Intervention Type: Drug
            Study Drug: Fenretinide
            Study Phase: Phase 1

            Summary: This study evaluates a fenretinide phospholipid suspension for the treatment of T-cell non-Hodgkin's lymphoma (NHL).

            Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon, in Patients with Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia, Lymphomas, or Histiocytic/Dendritic Cell Neoplasms

            Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon, in Patients with Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia, Lymphomas, or Histiocytic/Dendritic Cell Neoplasms

            Who is this study for: Adult patients with Multiple Myeloma, Acute Myeloid Leukemia, or Relapsed T Cell Lymphoma
            Enrollment Status: Recruiting
            Publish Date: December 11, 2024
            Intervention Type: Drug, Procedure, Biological
            Study Drugs: Cyclophosphamide, Ruxolitinib, Recombinant Vesicular Stomatitis Virus-Expressing Human Interferon Beta and Sodium-Iodide Symporter
            Study Phase: Phase 1

            Summary: This phase I trial studies the best dose and side effects of the VSV-hIFNβ-NIS vaccine with or without cyclophosphamide and combinations of ipilimumab, nivolumab, and cemiplimab in treating patients with multiple myeloma, acute myeloid leukemia or lymphoma that has come back after a period of improvement (relapsed) or that does not respond to treatment (refractory). VSV-IFNβ-NIS is a modified vers...

            Showing 1-3 of 3

            Last Updated: 06/27/2025