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Learn About Hereditary Spastic Paraparesis

What is the definition of Hereditary Spastic Paraparesis?
Hereditary spastic paraparesis is a term that refers to a group of genetic degenerative neurological disorders that affect the upper motor neurons, causing progressive weakness and spasticity of the legs. There are more than 80 different types of hereditary spastic paraparesis.
What are the symptoms of Hereditary Spastic Paraparesis?
Hereditary spastic paraparesis can be uncomplicated, complicated, or complex. Symptoms of hereditary spastic paraparesis depend on the subtype and usually appear in early childhood. Symptoms of hereditary spastic paraparesis include muscle weakness and spasticity in the legs; difficulty walking; toe drag; impaired vision; balance problems; seizures; cognitive impairment; peripheral neuropathy; deafness; knee, hip, back, and ankle pain; urinary urgency; difficulty swallowing; and speech difficulties.
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What are the current treatments for Hereditary Spastic Paraparesis?
Treatment for hereditary spastic paraparesis depends on the subtype and symptoms. Treatment for hereditary spastic paraparesis may include watchful waiting; exercise; physical therapy; muscle-relaxing medications, such as Lioresal, baclofen, or botulinum toxin; oxybutynin; and orthotics.
Who are the top Hereditary Spastic Paraparesis Local Doctors?
Elite in Hereditary Spastic Paraparesis
Elite in Hereditary Spastic Paraparesis
Milan, IT 

Marina Scarlato practices in Milan, Italy. Ms. Scarlato and is rated as an Elite expert by MediFind in the treatment of Hereditary Spastic Paraparesis. Her top areas of expertise are Hereditary Spastic Paraparesis, Spastic Paraparesis, Spastic Paraplegia Type 7, and Spastic Paraplegia Type 2.

Elite in Hereditary Spastic Paraparesis
Elite in Hereditary Spastic Paraparesis
Bosisio Parini, IT 

Maria Bassi practices in Bosisio Parini, Italy. Ms. Bassi and is rated as an Elite expert by MediFind in the treatment of Hereditary Spastic Paraparesis. Her top areas of expertise are Hereditary Spastic Paraparesis, Spastic Paraparesis, Spastic Paraplegia Type 7, and Spastic Paraplegia Type 2.

 
 
 
 
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Elite in Hereditary Spastic Paraparesis
Elite in Hereditary Spastic Paraparesis
New Delhi, DL, IN 

Ayush Agarwal practices in New Delhi, India. Mr. Agarwal and is rated as an Elite expert by MediFind in the treatment of Hereditary Spastic Paraparesis. His top areas of expertise are Hereditary Spastic Paraparesis, Spastic Paraparesis, Subacute Sclerosing Panencephalitis, Thrombectomy, and Mastectomy.

What are the latest Hereditary Spastic Paraparesis Clinical Trials?
Enhancement of Quality of Work And Life: A Personalised Primary Preventive Work Intervention to Enhance Sustainable Work Participation in Persons With Neurodegenerative Movement Disorders

Summary: Work participation is essential for quality of life, providing purpose, social interaction, financial security, and shaping social status. Work participation is increasingly compromised in people with slowly progressive chronic disorders (hereafter referred to as progressive disorders). This negatively impacts their quality of life. Early work-related support, focused on sustainable work-retention...

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Surgical Outcomes of Foot Deformities in Hereditary Spastic Paraplegia: A Prospective Cohort Study

Summary: Through a prospective cohort study, we aim to dynamically evaluate the long-term benefits and risks associated with surgical interventions for hereditary spastic paraparesis (HSP) accompanied by foot deformities. Our goal is to systematically summarize clinical experiences to guide practice and ultimately optimize patient outcomes. The core research objectives include elucidating: 1. the long-term...