Learn About Hyper IGE Syndrome
- Hyper IgE syndrome
- HIES
- Hyper-IgE recurrent infection syndrome
- Hyperimmunoglobulin E syndrome
Andrew Gennery practices in Newcastle Upon Tyne, United Kingdom. Mr. Gennery and is rated as an Elite expert by MediFind in the treatment of Hyper IGE Syndrome. His top areas of expertise are Severe Combined Immunodeficiency (SCID), Primary Immunodeficiency (PID), Chronic Granulomatous Disease, Bone Marrow Transplant, and Heart Transplant.
Bodo Grimbacher practices in Hannover, Germany. Grimbacher and is rated as an Elite expert by MediFind in the treatment of Hyper IGE Syndrome. Their top areas of expertise are Common Variable Immune Deficiency, Hyper IGE Syndrome, Autosomal Dominant Hyper IgE Syndrome, Primary Immunodeficiency (PID), and Bone Marrow Transplant.
Biman Saikia practices in Chandigarh, India. Saikia and is rated as an Elite expert by MediFind in the treatment of Hyper IGE Syndrome. Their top areas of expertise are Autosomal Dominant Hyper IgE Syndrome, Hyper IGE Syndrome, Allergic Bronchopulmonary Aspergillosis, Aspergillosis, and Kidney Transplant.
Summary: The Hyper IgE Syndromes (HIES) are primary immunodeficiencies resulting in eczema and recurrent skin and lung infections. Autosomal dominant Hyper IgE syndrome (AD-HIIES; Job's syndrome) is caused by STAT3 mutations, and is a multi-system disorder with skeletal, vascular, and connective tissue manifestations. Understanding how STAT3 mutations cause these diverse clinical manifestations is critical...
Background: -DOCK8 deficiency is a genetic disorder that affects the immune system and can lead to severe recurrent infections and possible death from infections or certain types of cancers, including blood cancers. A stem cell transplant is a life-saving treatment for this condition. In this study we are evaluating the efficacy and safety of transplant from different donor sources for DOCK8 deficiency. The d...
Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center