Non-Alcoholic Fatty Liver Disease Overview
Learn About Non-Alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is a buildup of excessive fat in the liver that can lead to liver damage resembling the damage caused by alcohol abuse, but that occurs in people who do not drink heavily. The liver is a part of the digestive system that helps break down food, store energy, and remove waste products, including toxins. The liver normally contains some fat; an individual is considered to have a fatty liver (hepatic steatosis) if the liver contains more than 5 to 10 percent fat.
The specific causes of NAFLD are unclear. Genetic variations and environmental factors contribute to the development of this complex disorder.
Common conditions include: Nonalcoholic Steatohepatitis (NASH)
NAFLD is a very common disorder, occurring in about 25 percent of the global population. Its prevalence is increasing along with the rising prevalence of obesity in industrialized societies, and it is now the most common chronic liver disorder in Western countries, including the United States. NAFLD is more prevalent in individuals of Hispanic, Native American, or Asian ancestry than in individuals of European or African ancestry.
An increased risk of developing NAFLD can be passed through generations in families, but the inheritance pattern is unknown. Variations in several genes as well as lifestyle and environmental factors contribute to the risk of developing this complex disorder.
Mayo Clinic
Manal Abdelmalek is a Hepatologist in Rochester, Minnesota. Dr. Abdelmalek and is rated as an Elite provider by MediFind in the treatment of Non-Alcoholic Fatty Liver Disease. Her top areas of expertise are Nonalcoholic Steatohepatitis (NASH), Non-Alcoholic Fatty Liver Disease, Cirrhosis, Enlarged Liver, and Liver Transplant. Dr. Abdelmalek is currently accepting new patients.
University Of Chicago
Mary Rinella is a Hepatologist in Chicago, Illinois. Dr. Rinella and is rated as an Elite provider by MediFind in the treatment of Non-Alcoholic Fatty Liver Disease. Her top areas of expertise are Non-Alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis (NASH), Cirrhosis, Liver Transplant, and Endoscopy. Dr. Rinella is currently accepting new patients.
University Of Texas Southwestern Medical Center At Dallas
Lisa Vanwagner is a Gastroenterologist in Dallas, Texas. Dr. Vanwagner and is rated as an Elite provider by MediFind in the treatment of Non-Alcoholic Fatty Liver Disease. Her top areas of expertise are Non-Alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis (NASH), Liver Failure, Liver Transplant, and Kidney Transplant.
Summary: This study is open to adults who are at least 18 years old and have: * A confirmed liver disease called non-alcoholic steatohepatitis (NASH) or * A confirmed liver disease called metabolic-associated steatohepatitis (MASH) * BMI of 27 kg/m2 or more or * 25 kg/m2 or more if the participant is Asian. People with a history of other chronic liver diseases or high alcohol intake cannot take part in thi...
Summary: The goal of this study is to assess the safety and efficacy of GSK4532990 in participants with alcohol-related liver disease.
Published Date: November 01, 2016
Published By: National Institutes of Health